Utility of an objective dyskinesia rating scale for Parkinson's disease: Inter‐ and intrarater reliability assessment
Identifieur interne : 005A67 ( Main/Exploration ); précédent : 005A66; suivant : 005A68Utility of an objective dyskinesia rating scale for Parkinson's disease: Inter‐ and intrarater reliability assessment
Auteurs : Goetz [États-Unis] ; G. T. Stebbins [États-Unis] ; H. M. Shale [États-Unis] ; A. E. Lang [Canada] ; D. A. Chernik [États-Unis] ; T. A. Chmura [États-Unis] ; J. E. Ahlskog [États-Unis] ; E. E. Dorflinger [États-Unis]Source :
- Movement Disorders [ 0885-3185 ] ; 1994.
English descriptors
- KwdEn :
- Activities of Daily Living (classification), Antiparkinson Agents (therapeutic use), Disability Evaluation, Dopamine Agents (therapeutic use), Dyskinesia, Humans, Movement Disorders (classification), Movement Disorders (diagnosis), Movement Disorders (drug therapy), Neurologic Examination (drug effects), Neurologic Examination (statistics & numerical data), Observer Variation, Parkinson Disease (classification), Parkinson Disease (diagnosis), Parkinson Disease (drug therapy), Parkinson's disease, Rating scale, Reproducibility of Results, Videotape Recording.
- MESH :
- chemical , therapeutic use : Antiparkinson Agents, Dopamine Agents.
- classification : Activities of Daily Living, Movement Disorders, Parkinson Disease.
- diagnosis : Movement Disorders, Parkinson Disease.
- drug effects : Neurologic Examination.
- drug therapy : Movement Disorders, Parkinson Disease.
- statistics & numerical data : Neurologic Examination.
- Disability Evaluation, Humans, Observer Variation, Reproducibility of Results, Videotape Recording.
Abstract
Although dyskinesia is a frequent and important problem in Parkinson's disease (PD), a reliable assessment measure has not been thoroughly developed and tested. We modified the Obeso dyskinesia scale to creat an objective rating scale for dyskinesia assessment during activities of daily living. Thirteen physicians and 15 study coordinators involved in a clinical trial independently reviewed videotape segments of PD patients performing three tasks: walking, putting on a coat, and lifting a cup to the lips for drinking. Raters evaluated the severity of worst dyskinesia seen, the types of all dyskinesias seen, and the type of dyskinesia most associated with motoric disability. For all assessments, the total group showed statistically significant inter‐ and intrarater reliability. Physicians had a higher consistency than did coordinators, but for most measures the difference was not statistically significant. Physicians and coordinators found the scale easy to use and especially practical for rating dyskinesia severity and for identifying the most disabling dyskinesia. Dyskinesias can be assessed in clinical trials and warrant regular documentation.
Url:
DOI: 10.1002/mds.870090403
Affiliations:
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<term>Dyskinesia</term>
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<term>Movement Disorders (classification)</term>
<term>Movement Disorders (diagnosis)</term>
<term>Movement Disorders (drug therapy)</term>
<term>Neurologic Examination (drug effects)</term>
<term>Neurologic Examination (statistics & numerical data)</term>
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<term>Parkinson Disease (diagnosis)</term>
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<front><div type="abstract" xml:lang="en">Although dyskinesia is a frequent and important problem in Parkinson's disease (PD), a reliable assessment measure has not been thoroughly developed and tested. We modified the Obeso dyskinesia scale to creat an objective rating scale for dyskinesia assessment during activities of daily living. Thirteen physicians and 15 study coordinators involved in a clinical trial independently reviewed videotape segments of PD patients performing three tasks: walking, putting on a coat, and lifting a cup to the lips for drinking. Raters evaluated the severity of worst dyskinesia seen, the types of all dyskinesias seen, and the type of dyskinesia most associated with motoric disability. For all assessments, the total group showed statistically significant inter‐ and intrarater reliability. Physicians had a higher consistency than did coordinators, but for most measures the difference was not statistically significant. Physicians and coordinators found the scale easy to use and especially practical for rating dyskinesia severity and for identifying the most disabling dyskinesia. Dyskinesias can be assessed in clinical trials and warrant regular documentation.</div>
</front>
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